why you can't depend on food alone for essential nutrition
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Reason #9: Genetic weaknesses
We are all genetically and biochemically unique – not perfect but with some kind of
genetic weakness. For example, you might have a genetic abnormality in methionine
metabolism called homocystinuria (methionine is an amino acid required to make your body function).

In this case, taking large doses of vitamin B6 is a way to compensate for this weakness.
There are many possible genetic abnormalities which can be helped with dietary supplementation.

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